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History and Current Use of Antimicrobial Drugs in Veterinary Medicine

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  • Author: John F. Prescott1
  • Editors: Frank Møller Aarestrup2, Stefan Schwarz3, Jianzhong Shen4, Lina Cavaco5
  • VIEW AFFILIATIONS HIDE AFFILIATIONS
    Affiliations: 1: Department of Pathobiology, University of Guelph, Guelph, Ontario N1G 2W1, Canada; 2: Technical University of Denmark, Lyngby, Denmark; 3: Freie Universität Berlin, Berlin, Germany; 4: China Agricultural University, Beijing, China; 5: Statens Serum Institute, Copenhagen, Denmark
    • Source: microbiolspec December 2017 vol. 5 no. 6 doi:10.1128/microbiolspec.ARBA-0002-2017
  • Received 24 February 2017 Accepted 06 November 2017 Published 21 December 2017
  • J. F. Prescott, [email protected]
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  • Abstract:

    This chapter briefly reviews the history and current use of antimicrobials in animals, with a focus on food animals in the more economically developed countries. It identifies some of the differences between human medical and food animal use, particularly in growth promotional and “subtherapeutic” use of medically-important antibiotics in animals. The public health impact of the extensive use of antibiotics in food animals for these purposes, differences internationally in such usage, and the major changes in current practices now underway in agricultural use are summarized. The emerging framing of the dimensions of antimicrobial resistance within a “One Health” framework is focusing global efforts to address the antimicrobial resistance crisis in a collaborative manner. The rapidly evolving development and application of practices of antimicrobial stewardship in animal is a critical part of the huge global effort to address antimicrobial resistance. The outcome is still uncertain.

  • Citation: Prescott J. 2017. History and Current Use of Antimicrobial Drugs in Veterinary Medicine. Microbiol Spectrum 5(6):ARBA-0002-2017. doi:10.1128/microbiolspec.ARBA-0002-2017.

References

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2017-12-21
2020-02-23

Abstract:

This chapter briefly reviews the history and current use of antimicrobials in animals, with a focus on food animals in the more economically developed countries. It identifies some of the differences between human medical and food animal use, particularly in growth promotional and “subtherapeutic” use of medically-important antibiotics in animals. The public health impact of the extensive use of antibiotics in food animals for these purposes, differences internationally in such usage, and the major changes in current practices now underway in agricultural use are summarized. The emerging framing of the dimensions of antimicrobial resistance within a “One Health” framework is focusing global efforts to address the antimicrobial resistance crisis in a collaborative manner. The rapidly evolving development and application of practices of antimicrobial stewardship in animal is a critical part of the huge global effort to address antimicrobial resistance. The outcome is still uncertain.

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History and Current Use of Antimicrobial Drugs in Veterinary Medicine
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Citation: Prescott J. 2017. History and current use of antimicrobial drugs in veterinary medicine. microbiolspec 5(6): doi:10.1128/microbiolspec.ARBA-0002-2017
/content/microbiolspec/10.1128/microbiolspec.ARBA-0002-2017.fig1
FIGURE 1
Routes of exchange of between animals and humans. Note the areas where antimicrobial drug selection for resistance is most likely. The size of the circles or boxes does not indicate the extent of the scale of the movement. After Linton ( 26 ), modified by R. Irwin; reproduced with permission.
microbiolspec/5/6/ARBA-0002-2017-fig1_thmb.gif
microbiolspec/5/6/ARBA-0002-2017-fig1.gif
Image of FIGURE 1
FIGURE 1

Routes of exchange of between animals and humans. Note the areas where antimicrobial drug selection for resistance is most likely. The size of the circles or boxes does not indicate the extent of the scale of the movement. After Linton ( 26 ), modified by R. Irwin; reproduced with permission.

Source: microbiolspec December 2017 vol. 5 no. 6 doi:10.1128/microbiolspec.ARBA-0002-2017
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History and Current Use of Antimicrobial Drugs in Veterinary Medicine
[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/microbiolspec/10.1128/microbiolspec.ARBA-0002-2017-1,webId=/content/author/microbiolspec/10.1128/microbiolspec.ARBA-0002-2017-1,properties={foaf_givenname=John F., foaf_name=John F. Prescott, foaf_surname=Prescott, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/microbiolspec/10.1128/microbiolspec.ARBA-0002-2017-aff1]]}]]
Citation: Prescott J. 2017. History and current use of antimicrobial drugs in veterinary medicine. microbiolspec 5(6): doi:10.1128/microbiolspec.ARBA-0002-2017
/content/microbiolspec/10.1128/microbiolspec.ARBA-0002-2017.T1
TABLE 1
Historical time line of important events and trends in the use of antimicrobial drugs in animals, with emphasis on food animals
Generic image for table
TABLE 1

Historical time line of important events and trends in the use of antimicrobial drugs in animals, with emphasis on food animals

Source: microbiolspec December 2017 vol. 5 no. 6 doi:10.1128/microbiolspec.ARBA-0002-2017
/content/microbiolspec/10.1128/microbiolspec.ARBA-0002-2017.T2
TABLE 2
Suggested categorization of antimicrobial drugs for veterinary use ( 6 )
Generic image for table
TABLE 2

Suggested categorization of antimicrobial drugs for veterinary use ( 6 )

Source: microbiolspec December 2017 vol. 5 no. 6 doi:10.1128/microbiolspec.ARBA-0002-2017
/content/microbiolspec/10.1128/microbiolspec.ARBA-0002-2017.T3
TABLE 3
Historical time line of major reports and their conclusions or recommendations relating to the public health aspects of antimicrobial drug use in food animals
Generic image for table
TABLE 3

Historical time line of major reports and their conclusions or recommendations relating to the public health aspects of antimicrobial drug use in food animals

Source: microbiolspec December 2017 vol. 5 no. 6 doi:10.1128/microbiolspec.ARBA-0002-2017

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