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Pathogenesis — Thoughts from the Front Line

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  • Author: James P. Nataro1
  • Editors: Tyrrell Conway2, Paul Cohen3
    Affiliations: 1: University of Virginia; 2: Oklahoma State University, Stillwater, OK; 3: University of Rhode Island, Kingston, RI
  • Source: microbiolspec June 2015 vol. 3 no. 3 doi:10.1128/microbiolspec.MBP-0012-2014
  • Received 05 December 2014 Accepted 07 January 2015 Published 11 June 2015
  • James Nataro, [email protected]
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  • Abstract:

    The field of bacterial pathogenesis has advanced dramatically in the last decade. High throughput molecular technologies have empowered scientists as never before. However, there remain some limitations, misconceptions and ambiguities in the field that may bedevil even the experienced investigator. Here, I consider some of the unanswered questions that are not readily tractable to even the most powerful technology.

  • Citation: Nataro J. 2015. Pathogenesis — Thoughts from the Front Line. Microbiol Spectrum 3(3):MBP-0012-2014. doi:10.1128/microbiolspec.MBP-0012-2014.


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The field of bacterial pathogenesis has advanced dramatically in the last decade. High throughput molecular technologies have empowered scientists as never before. However, there remain some limitations, misconceptions and ambiguities in the field that may bedevil even the experienced investigator. Here, I consider some of the unanswered questions that are not readily tractable to even the most powerful technology.

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